These South Carolina experts are, as the English say, “spot on”.
We excerpt from the abstract of Velazquez et al Pharmacol Res. 2007 Apr 29 the following, taken from a report on the various isoforms of Protein Kinase C involved in pain. You already knew this first part, but it is nice to see the experts stating what we have long known. Every sentence is important here.
“Pain is the PRIMARY reason that people seek medical care. At present, chronic unremitting pain is the THIRD greatest health problem after heart disease and cancer. Chronic pain is an economic burden in lost wages, lost productivity, medical expenses, legal fees and compensation. Chronic pain is defined as a pain of greater than 2 months duration. It can be of inflammatory or neuropathic origin that can arise following nerve injury or in the ABSENCE of any apparent injury. Chronic pain is characterized by an altered pain perception that includes allodynia (a response to a normally non-noxious stimuli) and hyperalgesia (an exaggerated response to a normally noxious stimuli). This type of pain is often insensitive to the traditional analgesics or surgical intervention…”
We can only add not only is pain the primary reason people seek medical care, it is the least funded of the common illnesses as to research dollars allocated per capita, by quite some degree, exponentially. Chronic pain is, as Patrick Wall described it, a SILENT epidemic.
The article is worth reading because Velazquez et al distinguish between ordinary and neuropathic pain.