MAP kinase is a well known pain chemical and is discussed in multiple articles here. Ret links to MAPK.
No wonder pain patients have trouble communicating. So many terms around.
Everyone at this site has heard of MRI, and even functional MRI. fMRI measures 3D activity (typically oxygen consumption). A new technique, PNMS looks interesting.
One by one scientists set up the pain cascade of chemicals and attempt to knock them off.
If we identify painless people, it should help us identify the hidden paths of pain.