We have enough NMDA to teach us that we don’t want any NMDA. Since NMDA mediates aversive learning, aversive learning may yet eliminate itself. A conundrum of course, but for those with CP, so is life. Here is a quick review, once again, regarding NMDA
Some very fine researchers have differed sharply on precisely which sodium channel is the most important in pain.
Hereditary pain disorders are shedding new light on the role of sodium ion channels in pain. (There is insufficient room in this article to review the action of sodium channels, but you can find a great deal of related information using SEARCH at this site).
In the past, there has often been an attempt to link specific pain with specific lesions. New PET studies show this is not always the case, and possibly never fully the case.
More information from the surveys. If you don’t recognize yourself here, don’t get nervous. It is due to the incompleteness of information provided in many surveys, the variety of CP manifestations, as well as the poverty of language where nerve injury pain is concerned.
Snails do it and so do humans. They make MULTIPLE varieties of pain chemicals.