Agmatine

Agmatine is decarboxylated argenine. Argenine, a common amino acid, and agmatine are both found naturally in the body. Agmatine is found in small vesicles near the opposing surface of a nerve synapse. It is one of the new neuromodulators being studied.

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Evolutionary Development and Pain

As most people know by now, computers are binary. Classic joke: There are 10 kinds of people in the world, those who can speak binary and those who cannot. The transistors which make up computers are nothing but toggle switches. This is nothing to be ashamed of, since mankind itself is largely produced and maintained by the toggling genes, and the “noncoding” DNA which turns on “real” genes nearby, ie genes which make (code for) proteins.

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Blockbuster Article on Central Pain

How smart ARE these guys? We already have been blessed with an article just for painonline.com by Jeffrey Coull on chloride- ions. Now, Coull et al have completely blown away the pain world with a new finding published in Dec 15, 2005 Nature. The Canadians are already staffing the Johns Hopkins Neurosurgery department. How far ahead have these people gotten?

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Central Pain Update: latest version

Alan Hess, who has endured central pain for many years, has a gift for straightforwardness that is truly remarkable. There is simply no embellishment and so we feel what he is saying in a way that is both shocking and moving. One of the commentors said he had read nothing like it beside Primo Levi, a great compliment, since Levi is considered the finest writer on suffering who has ever lived. Alan types with difficulty, but the message has gotten out. Our readership has read this particular article more than any other at painonline. We are proud to know Alan, and pay tribute to his mother as well, for her tireless care.

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