Gamma amino butyric acid is a pain inhibitor. We have already discussed GABA(B)in the article on CREB. GABA(A) acts like the opposite side of the coin from Purine2 receptors, which are pain exciters, which are part of the nitric oxide (N0) pathway. GABA and P2 entities are normally in balance, but there is evidence of dysfunction between GABA(A) and Purine2(P2) receptors, in nerve injury pain.
Chemistry is a pain, but a pain we must go through to get rid of PAIN. Why is it discussed here? First, because doctors visit this site and we want to incite curiosity in them. Secondly, because even if you don’t get it, if you find your health professional is not with you in the matter of the reality of pain, perhaps this information will help. Don’t worry if you don’t understand it all. The general idea is what we are after, to help you appreciate what is going on in your body to cause CP. If you exert the effort to read this, you may never again feel ashamed to relate your symptoms to another person.
Thank you for completing the survey. This article derives from audience participation. We hope to add detailed descriptions of how nerve injury feels in the various organ systems and areas of the body. This will help give the range of sensations that can be experienced. Please send your descriptions to comments to this article. Include things which relieve the pain. Comments do not appear unless they have been edited. Names will be withheld unless you indicate otherwise.
Another touching contribution by the author. An afterthought submitted is the best introduction:
“What you see is not what you get. Our lives would be ugly indeed, as would we, if the pain showed. If we can believe what our eyes see, the human face, and others can believe what they do not see, the invisible pain, we can get along.”
The notion that radiology can image pain is an urban myth. Clinical medicine must not abdicate its role for the simple reason that radiology has a way to go before it can be used to rule in or rule out the existence of pain.